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Quality evaluation of guidelines, consensus and statements related to cardiovascular diseases

Published on Mar. 02, 2026Total Views: 26 times Total Downloads: 8 times Download Mobile

Author: QIAN Shichao YANG Yazhuo MEN Jiakun BAI Zhenggang

Affiliation: School of Public Affairs, Nanjing University of Science & Technology, Nanjing 210000, China

Keywords: Cardiovascular diseases Guidelines Consensus Statements Quality evaluation AGREE Ⅱ RIGHT

DOI: 10.12173/j.issn.1004-4337.202506063

Reference: Qian SC, Yang YZ, Men JK, Bai ZG. Quality evaluation of guidelines, consensus and statements related to cardiovascular diseases[J]. Journal of Mathematical Medicine, 2026, 39(2): 141-151. DOI: 10.12173/j.issn.1004-4337.202506063[Article in Chinese]

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Abstract

Objective  To systematically evaluate the quality of guidelines, consensus and statements related to cardiovascular diseases.

Methods  Multiple Chinese and English databases and official guideline platforms were searched, including CNKI, WanFang Data, Scopus, PubMed, National Institute for Health and Care Excellence (NICE) and American Heart Association (AHA) websites from January 2008 to July 2025. Two researchers independently assessed the methodological quality of guidelines, consensus and statements. The methodological rigor of guidelines, consensuses and statements were evaluated using the internationally recognized AGREE II scale, and the reporting normality of statements was evaluated based on the RIGHT list. To ensure the credibility of the evaluation results, the consistency of the scores among researchers was tested by calculating the intraclass correlation coefficient (ICC).

Results  A total of 21 guidelines, 11 consensus and 3 statements were included. According to the evaluation results of AGREE II, the included guidelines, consensus and statements performed best in the two domains of "scope and purpose" (96.89%) and "clarity of presentation" (95.91%), and the average standardization scores were all higher than 95%. The scores in the fields of "stakeholder involvement" (75.23%), "rigour of development" (77.06%) and "editorial independence" (71.29%) were at a medium level, while the score in the "applicability" field was relatively low (58.26%). Finally, 15 A-level and 20 B-level guidelines/consensuses/statements were selected. The average reporting rate of the RIGHT evaluation results was 58.95%, with the highest score in the "funding and conflict of interest statement and management" (90.00%) field. The scores in the three areas of "evidence" (56.66%), "recommendations" (34.00%) and "review and quality assurance" (58.33%) were relatively low. The scores in other areas, including "basic information" (67.50%), "background" (74.00%) and "other information" (66.67%), were at a medium level.

Conclusion  The methodological and reporting quality of guidelines, consensus and statements related to cardiovascular diseases need to be further improved. In the future, it is necessary to strictly follow international standards to formulate higher-quality guidelines, consensus and statements for cardiovascular diseases, and enhance the clinical applicability of recommendations.

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