Objective  Using high-resolution magnetic resonance vascular wall imaging (HRMR-VWI) technique to explore the efficacy of Qilong capsule combined with atorvastatin calcium and others on symptomatic vulnerable carotid plaque and the effect on lipid levels.

Methods  Patients who underwent carotid HRMR-VWI at Yantaishan Hospital for cerebral ischemic unilateral limb weakness from March 2020 to January 2023 were selected and randomly divided into a Western medicine treatment group (control group) and a Western medicine combined with Qilong capsule treatment group (experimental group), and were rechecked after 6 months to compare the HRMR-VWI measurements and lipid levels of the two groups.

Results  A total of 32 patients were included, 18 in the control group and 14 in the experimental group. Triglyceride level was significantly lower in the experimental group than that in the control group after treatment (1.07±0.38 vs. 1.84±1.24, P=0.033). Compared with pre-treatment, the distal normal vessel area and remodeling index increased in the control group, the lumen area at the narrowest point increased in the experimental group, and there was a decrease in lipid core area and triglycerides in both groups (P<0.05).

Conclusion  Qilong capsule combined with western drug therapy has significant lipid-lowering effect, improves carotid plaque stenosis, and reverses vascular remodeling effect to some extent.

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