Combined laparoscopic and endoscopic treatment of gastric schwannoma: a case report

Published on Nov. 01, 2025Total Views: 35 times Total Downloads: 6 times Download Mobile

Affiliation: 1. School of Medicine, Jianghan University, Wuhan 430056, China 2. Department of Gastrointestinal Surgery, Wuhan Fourth Hospital, Wuhan 430033, China

Keywords: Gastric schwannoma Laparoscopic and endoscopic cooperative surgery Immunohistochemistry

DOI: 10.12173/j.issn.1004-4337.202507053

Reference: Zou JJ, Xiao F. Combined laparoscopic and endoscopic treatment of gastric schwannoma: a case report[J]. Journal of Mathematical Medicine, 2025, 38(10): 787-792. DOI: 10.12173/j.issn.1004-4337.202507053[Article in Chinese]  Copied

Abstract
Full-text
References

Abstract

Gastric schwannoma (GS) is a rare mesenchymal tissue-derived tumor histologically originating from Schwann cells of the nerve sheath, which has a low incidence in clinical practice, accounting for only 0.2% of all gastric tumors. Surgical resection is currently the main treatment method of it. A case of GS resection by laparoscopic and endoscopic cooperative surgery (LECS) was reported in this paper. Combined with relevant literature review, the surgical treatment strategy of GS was systematically summarized, in order to provide reference for clinical gastric diagnosis and treatment.

Full-text

Please download the PDF version to read the full text: download

References

1.Qi Z, Yang N, Pi M, et al. Current status of the diagnosis and treatment of gastrointestinal schwannoma[J]. Oncol Lett, 2021, 21(5): 384. DOI: 10.3892/ol.2021.12645.

2.Pu C, Zhang K. Gastric schwannoma: a case report and literature review[J]. J Int Med Res, 2020, 48(9): 300060520957828. DOI: 10.1177/0300060520957828.

3.Khan S, Honganur NS, Kumar S, et al. Gastric schwannoma: a case report and literature review[J]. Cureus, 2022, 14(5): e24785. DOI: 10.7759/cureus.24785.

4.Cordeiro R, Morgado M, Oliveira V, et al. Gastric schwannoma: two case reports and review of the literature[J]. Radiol Case Rep, 18(12): 4465-4473. DOI: 10.1016/j.radcr.2023.09.048.

5.Dong W, Zhu J, Tan X, et al. Gastric schwannoma: a case report[J]. Asian J Surg, 2024, S1015-9584(24)02620-4. DOI: 10.1016/j.asjsur.2024.11.018.

6.Busta Nistal MR, Alcaide Suarez N, Fernández Salazar L, et al. Gastric schwannoma. Differential diagnosis of submucosal tumours[J]. Gastroenterol Hepatol, 2022, 45 Suppl 1: 58-59. DOI: 10.1016/j.gastrohep.2021.02.005.

7.王萍,陈光祥,舒健,等. 多层螺旋CT多期增强鉴别诊断胃神经鞘瘤与胃间质瘤[J]. 中国医学影像学杂志, 2023, 31(2): 155-159. [Wang P, Chen GX, Shu J, et al. Differential diagnosis of gastric schwannoma and gastric stromal tumor based on multiphase enhanced multi-slice spiral CT[J]. Chinese Journal of Medical Imaging, 2023, 31(2): 155-159. DOI: 10.3969/j.issn.1005-5185.2023.02.013.

8.Fujiwara S, Nakajima K, Nishida T, et al. Gastric schwannomas revisited: has precise preoperative diagnosis become feasible?[J]. Gastric Cancer, 2013, 16(3): 318-323. DOI: 10.1007/s10120-012-0186-x.

9.Takeda M, Amano Y, Machida T, et al. CT, MRI, and PET findings of gastric schwannoma[J]. Jpn J Radiol, 2012, 30(7): 602-605. DOI: 10.1007/s11604-012-0093-4.

10.Albshesh A, Kaufmann MI, Levy I. Gastric schwannoma[J]. Clin Gastroenterol Hepatol, 2020, 18(12): e142-e143. DOI: 10.1016/j.cgh.2019.08.027.

11.Bohlok A, El Khoury M, Bormans A, et al. Schwannoma of the colon and rectum: a systematic literature review[J]. World J Surg Oncol, 2018, 16(1): 125. DOI: 10.1186/s12957-018-1427-1.

12.Hong X, Wu W, Wang M, et al. Benign gastric schwannoma: how long should we follow up to monitor the recurrence? A case report and comprehensive review of literature of 137 cases[J]. Int Surg, 2015, 100(4): 744-747. DOI: 10.9738/INTSURG-D-14-00106.1.

13.Nishida T, Blay JY, Hirota S, et al. The standard diagnosis, treatment, and follow-up of gastrointestinal stromal tumors based on guidelines[J]. Gastric Cancer, 2016, 19(1): 3-14. DOI: 10.1007/s10120-015-0526-8.

14.Zhong Z, Xu Y, Liu J, et al. Clinicopathological study of gastric schwannoma and review of related literature[J]. BMC Surg, 2022, 22(1): 159. DOI: 10.1186/s12893-022-01613-z.

15.Li J, Chen JH, Huang WF, et al. Gastric schwannoma: a retrospective analysis of clinical characteristics, treatments, and outcomes[J]. Asian J Surg, 2024, 47(1): 407-412. DOI: 10.1016/j.asjsur.2023.09.042.

16.Huang JL, Zheng ZH, Wei HB, et al. Endoscopy-assisted laparoscopic resections for gastric gastrointestinal stromal tumors: a retrospective study[J]. J Laparoendosc Adv Surg Tech A, 2017, 27(2): 110-114. DOI: 10.1089/lap.2016.0068.

17.Kikuchi S, Nishizaki M, Kuroda S, et al. Nonexposure laparoscopic and endoscopic cooperative surgery (closed laparoscopic and endoscopic cooperative surgery) for gastric submucosal tumor[J]. Gastric Cancer, 2017, 20(3): 553-557. DOI: 10.1007/s10120-016-0641-1.

18.Mitsui T, Niimi K, Yamashita H, et al. Non-exposed endoscopic wall-inversion surgery as a novel partial gastrectomy technique[J]. Gastric Cancer, 2014, 17(3): 594-599. DOI: 10.1007/s10120-013-0291-5.

19.侯康,宋丹琳,李凯园,等. 双镜联合切除胃神经鞘瘤1例报道并文献复习[J]. 胃肠病学和肝病学杂志, 2022, 31(3): 359-360. [Hou K, Song DL, Li KY, et al. CLER of gastric schwannoma: one case report and literature review[J]. Chinese Journal of Gastroenterology and Hepatology, 2022, 31(3): 359-360.] DOI: 10.3969/j.issn.1006-5709.2022.03.027.

20.高玉海,严强,许洪宝,等. 双镜联合与开腹手术治疗胃间质瘤疗效与安全性比较的Meta分析[J]. 浙江医学, 2017, 39(24): 2236-2240. [Gao YH, Yan Q, Xu HB, et al. Efficacy and safety of laparoscopic and endoscopic cooperative surgery versus open resection for gastric stromal tumors: a Meta-analysis[J]. Zhejiang Medical Journal, 2017, 39(24): 2236-2240.] DOI: 10.12056/j.issn.1006-2785.2017.39.24.2016-1691.