Objective  To investigate the effects of ultrasound-guided quadratus lumborum block combined with nalbuphine in analgesia after caesarean section.

Methods  Primiparas who underwent cesarean section in the department of obstetrics at Shenzhen Baoan Maternal and Child Healthcare Hospital from April 2021 to April 2022 were selected as the research subjects, and were divided into a study group and a control group based on random number table method. The control group underwent nalbuphine venous patient-controlled intravenous analgesia (PCIA) after surgery, and the study group underwent ultrasound-guided quadratus lumborum block combined nalbuphine. The mean arterial pressure (MAP) and heart rate (HR) of the two groups were observed before surgery and at 4 h, 8 h, 12 h and 24 h after surgery, visual analogue score (VAS) was used to evaluate the pain of incision at 4 h, 8 h, 12 h and 24 h after surgery, and the Ramsay sedation score was used to evaluate the postoperative sedation status and understand the application of analgesic pumps.

Results  A total of 110 participants were enrolled, with 55 cases each in the study group and the control group. Compared with the control group, the HR, MAP and VAS scores of 4 h, 8 h, 12 h, and 24 h after surgery were significantly reduced (P<0.05), and the Ramsay scores of sedation 1 h and 6 h after surgery were increased (P<0.05). The first compression time of the analgesia pump in the study group was greater than that of the control group, and the effective compression of the analgesia pump within 24 hours after surgery was less than that of the control group (P<0.05).

Conclusion  Ultrasound-guided quadratus lumborum block combined with nalbuphine in post-cesarean analgesia can effectively reduce postoperative pain, and has a good postoperative sedation effect.

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