Objective  To analyze the epidemiological characteristics of hand foot mouth disease deaths in Hubei Province to provide a reference basis for preventing and reducing the death cases.

Methods  Case information of hand foot mouth disease in Hubei Province from 2008 to 2021 was collected, and the epidemiology, medical institution and etiology were analyzed by descriptive methods.

Results  Hubei province reported 981 315 cases and 112 deaths from 2008 to 2021, case fatality rate was 0.0114%. The peak of disease is distributed in April to June, and the death cases are mainly concentrated in April to July. The deaths were distributed in 40 (38.83%) districts and counties of the the province. The male to female ratio was 2.03∶1, the median age was 1 year, 98.21% (110/112) were under 5 years old, and 91.07% (102/112) were scattered children. The etiology examination results were mainly EV71 (95.65%, 88 / 92).

Conclusion  The overall death of HFMD shows a downward trend, however the epidemiological investigation and etiology detection of severe death cases should be strengthened and improve the timeliness of diagnosis and treatment to avoid death.

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