The influencing factors of diabetes mellitus after liver transplantation: best evidence summary

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Author:  LOU Lianyu ^1, ² ZHANG Bingliang ¹ ZHANG Shuai ¹ CHENG Lijie ¹ XU Qingguo ¹

Affiliation: 1. Department of Liver Transplantation, The Affiliated Hospital of Qingdao University, Qingdao 266000, Shandong Province, China 2. School of Nursing, Qingdao University, Qingdao 266021, Shandong Province, China

Keywords: Liver transplantation Diabetes mellitus Influencing factors Evidence-based nursing Evidence summary

DOI: 10.12173/j.issn.1004-4337.202503046

Reference: Lou LY, Zhang BL, Zhang S, Cheng LJ, Xu QG. The influencing factors of diabetes mellitus after liver transplantation: best evidence summary[J]. Journal of Mathematical Medicine, 2025, 38(9): 694-701. DOI: 10.12173/j.issn.1004-4337.202503046[Article in Chinese]  Copied

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Abstract

Objective To systematically search, evaluate and integrate the relevant evidence on the influencing factors of diabetes mellitus after liver transplantation, to help medical staff identify high-risk groups of diabetes mellitus after liver transplantation as early as possible, and to provide references for the prevention and management of diabetes mellitus after liver transplantation.

Methods Based on the "6S" evidence-based framework, a systematic search was conducted on both domestic and foreign guideline websites (such as GIN, Medlive, etc.), evidence-based medicine center official websites, medical association websites and databases, and the search time period was from the establishment of databases to April 2025. Joanna Briggs Institute (JBI) evidence-based trained researchers independently assessed the quality of the literature and extracted evidence, and cross-checked to ensure consistency.

Results A total of 10 articles were included, including 1 guideline, 3 diagnosis and treatment standards, 4 expert consensuses, 1 evidence summary and 1 systematic review. 35 pieces of evidence related to the influencing factors of diabetes mellitus after liver transplantation were summarised from three perspectives: patients' general conditions, disease-related indicators and treatment-related indicators.

Conclusion This study summarized the best evidence of the influencing factors of diabetes mellitus after liver transplantation, providing targeted evidence-based application reference for clinicians.

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