Objective  To explore the willingness to receive influenza vaccines and its influencing factors among parents of Chinese children.

Methods  Relevant literature on the willingness to receive influenza vaccines and its influencing factors of Chinese parents were systematically searched from PubMed, Web of Science, Embase, the Cochrane Library, WanFang Data, CBM, CNKI and VIP from the establishment of databases to March 2024. Two researchers independently screened the literature and extracted data, and Stata 18.0 software was used for Meta-analysis.

Results  A total of 27 articles were included, including 111 169 children's parents, 70 340 of whom had the willingness to receive influenza vaccines, involving a total of 36 influencing factors. The results of Meta-analysis showed that the willingness rate of parents of Chinese children to receive influenza vaccines was 64.7% (95%CI: 58.7%-70.6%). The results of subgroup analysis showed that there were statistically significant differences in the willingness rate to receive influenza vaccines among parents of children in different survey time, study area, urban economic level, children's age, survey method and survey location (P<0.05). The age of the parents was 30-40 years old (OR=0.808, 95%CI: 0.745-0.875) and over 40 years old (OR=0.597, 95%CI: 0.408-0.875), and the gender of the parents was female (OR=0.764, 95%CI: 0.657-0.888) are the risk factors of vaccination willingness (P<0.05). Thought the vaccine was safe (OR=1.782, 95%CI: 1.443-2.200), thought the vaccine was effective (OR=2.165, 95%CI: 1.494-3.140), had a history of influenza vaccination (OR=2.880, 95%CI: 1.798-4.613), had a history of influenza (OR=2.317, 95%CI: 1.016-5.283), not worried about the side effects of influenza vaccines (OR=2.232, 95%CI: 1.729-2.880), recommended vaccination by medical staff (OR=1.357, 95%CI: 1.122-1.642), aware of influenza vaccines (OR=3.242, 95%CI: 2.210-4.755), low or free vaccine price (OR=2.061, 95%CI: 1.250-3.398), had time to vaccinate and the vaccination site was close to home (OR=1.714, 95%CI: 1.254-2.344), thought it should be vaccinated every year (OR=3.666, 95%CI: 1.790-7.506), recommended vaccination by family and friends (OR=6.203, 95%CI: 3.881-9.914) and thought that children were susceptible to influenza (OR=2.390, 95%CI: 1.202-4.754) are the postitive factors of vaccination willingness (P<0.05).

Conclusion  The willingness to receive influenza vaccines of parents of Chinese children should be improved. Parents' age and gender, the safety and effectiveness of vaccines, influenza vaccination history, influenza history, side effects, whether health care workers recommend influenza vaccines, knowledge of influenza vaccines, vaccine price, time/distance, whether it should be vaccinated every year, whether it is recommended that family and friends should be vaccinated, and whether children are susceptible to influenza were the main factors influencing parents' willingness to receive influenza vaccines in China. Efforts should be made to actively promote and popularize knowledge about vaccination, in order to increase the willingness rate to receive influenza vaccines of children's parents.

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