Objective  To study the influencing factors of COVID-19 vaccine hes-itancy and to analyze the correlation between knowledge, health belief and COVID-19 vaccine hesitancy.

Methods  From June 21 to July 10, 2022, permanent residents aged 18 and above in Fuming Subdistrict of Ningbo were selected through the National Health Information Platform of Ningbo City, and the survey subjects were selected by systematic sampling method, and the online questionnaire survey was conducted through the smart public health system. Multivariate logistic regression was used to analyze the influencing factors of vaccine hesitancy. Spearman correlation analysis was used to explore the correlation between knowledge, health belief and COVID-19 vaccine hesitancy, and Bootstrap mediation analysis was used to explore the relationship among them.

Results  The COVID-19 vaccine hesitancy rate of 1,049 respondents was 7.82% (95%CI 6.19% to 9.44%), people aged 18-35 were more likely to have COVID-19 vaccine hesitancy than those aged 36-59, and people who had not received influenza vaccine in the past two years were more likely to have COVID-19 vaccine hesitancy. Health beliefs played a complete mediating role in the influence of knowledge on COVID-19 vaccine hesitancy.

Conclusion  Different interventions for different pop-ulations are very important for improving health literacy and reducing vaccine.

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