A case of immune myositis and peripheral neuropathy induced by immune checkpoint inhibitor

Published on May. 06, 2023Total Views: 1565 times Total Downloads: 563 times Download Mobile

Author: Tian-Zi XU Teng-Fei WANG Yi-Xin LIU  Yong-Chang WEI

Affiliation: Department of Gastrointestinal Tumors Radiation and Medical Oncology, Zhongnan Hospital of Wuhan University, Wuhan 430071, China

Keywords: Immune checkpoint inhibitors Immune myositis Peripheral neuropathy Perihilar cholangiocarcinoma

DOI: 10.12173/j.issn.1004-4337.202303118

Reference: Xu TZ, Wang TF, Liu YX, Wei YC. A case of immune myositis and peripheral neuropathy induced by immune checkpoint inhibitor[J]. Journal of Mathematical Medicine, 2023, 36(4): 316-320. DOI: 10.12173/j.issn.1004-5511.202303118[Article in Chinese]  Copied

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Abstract

A retrospective analysis of the diagnosis and treatment of a patients with advanced perihilar cholangiocarcinoma with immunodeficiency and peripheral neuropathy induced by terbutal-ine was conducted, and clinical features and principles of diagnosis and treatment were summarized in combination with relevant literature on immune checkpoint inhibitors. In the application of antitumor immunotherapy, clinicians should closely monitor relevant indicators of the patients and be alert to the occurrence of immune-related adverse reactions so that early diagnosis and intervention can be made. The discontinuation of immunotherapy and the use of corticosteroids and/or immunosuppressant therapy are critical to the prognosis of patients with immune-related adverse events (irAEs).

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