A review of research on Charcot neuropathic osteoarthropathy in the past decade

Published on Jun. 05, 2023Total Views: 1821 times Total Downloads: 606 times Download Mobile

Author: Xiao-Ting LIU ¹  Yu-Suo GONG ² Bao-Hua YUAN ¹ Jia-Ru GUANG ³ Yu-Quan WANG ²

Affiliation: Kang HUANG1, Tong-Ke LIU1, Fu-Ping KANG1, Chen YANG2, Xi-Yan LYU2 1. Clinical College of Chinese Medicine, Gansu University of Chinese Medicine, Lanzhou 730000, China 2. Department of Orthopedics, Gansu Provincial Hospital of Traditional Chinese Medicine, Lanzhou 730000, China 3. Sports Science and Technology Center of Ningxia Hui Autonomous Region, Yinchuan 750001, China

Keywords: Charcot neuropathic osteoarthropathy Hypalgesia Overview

DOI: 10.12173/j.issn.1004-4337.202303059

Reference: Liu XT, Gong YS, Yuan BH, Guang JR, Wang YQ, Huang K, Liu TK, Kang FP, Yang C, Lyu XY. A review of research on Charcot's joint disease in the past decade[J]. Journal of Mathematical Medicine, 2023, 36(5): 385-391. DOI:10.12173/j.issn.1004-4337.202303059[Article in Chinese]  Copied

Abstract
Full-text
References

Abstract

Objective To investigate the stage, mechanism, imaging studies, clinical mani-festations at the onset site, and treatment direction of Charcot neuropathic osteoarthropathy (CN).

Methods The clinical data of CN were analyzed, and relevant literatures published at home and abroad from 2011 to 2022 were retrieved, and the studies were analyzed one by one to summarize their clinical manifestations, treatment methods and follow-up prognosis.

Results 302 articles were searched and 11 articles were ultimately included. CN has a complex pathogenesis and involves many foot and ankle pathologies in clinic in patients with a history of diabetes mellitus; spinal cord injury (SCI), spinal TB with multiple spinal involvement. Syphilis infection has a predilection for the knee, followed by the hip. Syringomyelia neuropathy mostly occurs in the shoulder, followed by the elbow and wrist joints.

Conclusion The principle of management of patients with CN is to control the original disease uneventfully before proceeding with management of the lesion site.

Full-text

Please download the PDF version to read the full text: download

References

1.谢利秋, 李咏梅. 糖尿病性夏科氏关节病的影像学研究进展[J]. 磁共振成像, 2019, 10(3): 228-231. [Xie LQ, Li YM. Research progresses in imaging of charcot neuropathic osteoarthropathy in diabetic foot[J]. Chinese Journal of Magnetic Resonance Imaging, 2019, 10(3): 228-331.] DOI: 10.12015/issn.1674-8034.2019.03.014.

2.黄杰, 王绍武, 邓小丽, 等. 脊髓空洞症并发左肩关节夏科关节病1例[J]. 中国医学影像技术, 2016, 32(6): 993. [Huang J, Wang SW, Deng XL, et al. Left shoulder Charcot arthropathy combined with syringomyelia: case report[J]. Chinese Journal of Medical Imaging Technology, 2016, 32(6): 993.] DOI: 10.13929/j.1003-3289.2016.06.048.

3.殷汉, 杨兵全, 孙子林. 炎症在糖尿病夏科足发病机制中的作用[J]. 中华糖尿病杂志, 2015, 7(7): 452-454. [Yin H, Yang BQ, Sun ZL. The role of inflammation in the pathogenesis of diabetes Charcot foot[J]. Chinese Journal of Diabetes, 2015, 7(7): 452-454.] DOI: 10.3760/cma.j.issn.1674-5809.2015.07.012.

4.Jeffcoate W. Vascular calcification and osteolysis in diabetic neuropathy-is RANK-L the missing link?[J]. Diabetologia, 2004, 47(9): 1488-1492. DOI: 10.1007/s00125-004-1477-5.

5.Wang G, Lin J, Zhang H, et al. Three-dimension correction of Charcot ankle deformity with a titanium implant[J]. Comput Assist Surg (Abingdon), 2021, 26(1): 15-21. DOI: 10.1080/24699322.2021.1887356.

6.张景义, 孟令宇, 吴雪静, 等. 1型糖尿病并发夏科足一例报告并文献复习[J]. 中国全科医学, 2015, 18(31): 3885-3887. [Zhang JY, Meng LY, Wu XJ, et al. Type 1 diabetes mellitus complicated with Charcot foot: a case report and literature review[J]. Chinese General Practice, 2015, 18(31): 3885-3887.] DOI: 10.3969/j.issn.1007-9572.2015.31.027.

7.Kim SI, Kim YH, Lee JW, et al. Rheumatoid arthritis-associated spinal neuroarthropathy with double-level isthmic spondylolisthesis[J]. Eur Spine J, 2019, 28(9): 2145-2150. DOI: 10.1007/s00586-017-5220-6.

8.李冬松, 李叔强, 冯卫, 等. 三期梅毒感染合并神经性髋关节病一例报告[J]. 中华骨科杂志, 2012, 32(8): 794-795. [Li DS, Li SQ, Feng W, et al. A case report of stage III syphilis infection combined with neuropathic hip joint disease[J]. Chinese Journal of Orthopedics, 2012, 32(8): 794-795.] DOI: 10.3760/cma.j.issn.0253-2352.2012.08.016.

9.Lu Y, Xiang JY, Shi CY, et al. Cervical spondylotic myelopathy with syringomyelia presenting as hip Charcot neuroarthropathy: a case report and review of literature[J]. World J Clin Cases, 2022, 10(3): 1077-1085. DOI: 10.12998/wjcc.v10.i3.1077.

10.Memarpour R, Tashtoush B, Issac L, et al. Syringomyelia with Chiari I malformation presenting as hip charcot arthropathy: a case report and literature review[J]. Case Rep Neurol Med, 2015, 2015: 487931. DOI: 10.1155/2015/487931.

11.Allo Miguel G, García Fernández E, Hawkins Carranza F. Diabetic Charcot neuroarthropathy of the knee in a patient with type-1 diabetes mellitus[J]. Endocrine, 2015, 49(3): 863-864. DOI: 10.1007/s12020-014-0466-9.

12.Hernigou J, Boulares S, Delahaut O. Spontaneous posterior shoulder dislocation as the first symptom of a Charcot arthropathy[J]. Acta Orthop Belg, 2018, 84(1): 73-77. https://pubmed.ncbi.nlm.nih.gov/30457503/.

13.唐辉, 徐永清, 汤逊, 等. Chiari畸形I型合并脊髓空洞症、双肘Charcot关节病1例[J]. 西南国防医药, 2016, 26(12): 1544-1546. [Tang H, Xu YQ, Tang X, et al. Chiari malformation type I combined with syringomyelia and double elbow Charcot arthropathy: case report[J]. Medical Journal of National Defending Forces in Southwest China, 2016, 26(12): 1544-1546.] DOI: 10.3969/j.issn.1004-0188.2016.12.069.

14.Nozaka K, Miyakoshi N, Yuasa Y, et al. Simultaneous total knee arthroplasty and ankle arthrodesis for charcot neuroarthropathy[J]. Case Rep Orthop, 2019, 2019: 6136409. DOI: 10.1155/2019/6136409.

15.Xie XH, Tang JG, Liu ZH, et al. Case report: mutant SCN9A susceptible to charcot neuroarthropathy in a patient with congenital insensitivity to pain[J]. Front Neurosci, 2021, 15: 697167. DOI: 10.3389/fnins.2021.697167.

16.Jeffcoate W, Lima J, Nobrega L. The Charcot foot[J]. Diabet Med, 2000, 17(4): 253-258. DOI: 10.1046/j.1464-5491.2000.00233.

17.Chaudhary S, Bhansali A, Rastogi A. Mortality in Asian Indians with Charcot's neuroarthropathy: a nested cohort prospective study[J]. Acta Diabetol, 2019, 56(12): 1259-1264. DOI: 10.1007/s00592-019-01376-9.

18.甘美舍, 黄艳, 杨斌. 不同溃疡程度糖尿病足患者的临床特点及预后分析[J]. 糖尿病新世界, 2020, 23(1): 161-162. [Gan MS, Huang Y, Yang B. Clinical characteristics and prognosis analysis of diabetes foot patients with different ulcer degrees[J]. Diabetes New World, 2020, 23(1): 161-162.] DOI: 10.16658/j.cnki.1672-4062.2020.01.161.

19.Durgia H, Sahoo J, Kamalanathan S, et al. Role of bisphosphonates in the management of acute Charcot foot[J]. World J Diabetes, 2018, 9(7): 115-126. DOI: 10.4239/wjd.v9.i7.115.

20.Carves S, Bourgeon-Ghittori M, Henry J, et al. Denosumab in active Charcot neuro-osteoarthropathy of the foot[J]. Joint Bone Spine, 2021, 88(6): 105241. DOI: 10.1016/j.jbspin.2021.105241.

21.Rastogi A, Bhansali A, Jude EB. Efficacy of medical treatment for Charcot neuroarthropathy: a systematic review and meta-analysis of randomized controlled trials[J]. Acta Diabetol, 2021, 58(6): 687-696. DOI: 10.1007/s00592-020-01664-9.

22.阳诚, 许樟荣, 邓武权, 等. 糖尿病夏科足的诊治进展[J]. 中华糖尿病杂志, 2022, 14(4): 316-320. [Yang C, Xu ZR, Deng WQ, et al. Diagnosing and treatment for diabetic Charcot foot[J]. Chinese Journal of Diabetes, 2022, 14(4): 316-320.] DOI: 10.3760/cma.j.cn115791-20210620-00348.

23.陆清达, 刘趁心, 王晓明, 等. 机器人辅助关节融合术治疗儿童足夏科关节病1例[J]. 中国临床案例成果数据库, 2022, 4(1): E01581-E01581. [Lu QD, Liu CX, Wang XM, et al. Robot-assisted ofarthrodesis of Charcot's ar-thropathy in children:a case report and literatures review[J]. Chinese Medical Case Repository, 2022, 4(1): E01581-E01581.] DOI: 10.3760/cma.j.cmcr.2022.e01581.

24.徐文斌, 邓红平, 胡灏, 等. 脊柱夏科氏关节病的诊断与治疗[J]. 中华骨科杂志, 2021, 41(1): 43-48. [Xu WB, Deng HP, Hu H, et al. Diagnosis and treatment of Charcot spinal arthropathy[J]. Chinese Journal of Orthopedics, 2021, 41(1): 43-48.] DOI: 10.3760/cma.j.cn121113-20201023-00616.

25.Solinsky R, Donovan JM, Kirshblum SC. Charcot Spine following chronic spinal cord injury: an analysis of 201 published cases[J]. Spinal Cord, 2019, 57(2): 85-90. DOI: 10.1038/s41393-018-0216-6.

26.刘旭, 苏日力格, 高航, 等. 全髋关节置换术治疗脊髓痨性夏科氏髋关节病1例报告[J]. 实用骨科杂志, 2018, 24(12): 1151-1152. [Liu X, Su RLG, Gao H, et al. A case report of total hip arthroplasty for the treatment of spinal tuberculosis associated Charcot's hip arthropathy[J]. Journal of Practical Orthopedics, 2018, 24(12): 1151-1152.] DOI: 10.13795/j.cnki.sgkz.2018.12.028.

27.Habib GS, Saliba W, Nashashibi M. Local effects of intra-articular corticosteroids[J]. Clin Rheumatol, 2010, 29(4): 347-356. DOI: 10.1007/s10067-009-1357-y.

28.Siddiqui NA, Millonig KJ, Mayer BE, et al. Increased arthrodesis rates in Charcot neuroarthropathy utilizing distal tibial distraction osteogenesis principles[J]. Foot Ankle Spec, 2022, 15(4): 394-408. DOI: 10.1177/19386400221087822.

29.Lu V, Zhang J, Thahir A, et al. Charcot knee - presentation, diagnosis, management - a scoping review[J]. Clin Rheumatol, 2021, 40(11): 4445-4456. DOI: 10.1007/s10067-021-05775-8.

30.庄至坤, 许志庆, 林行会, 等. 可旋转铰链膝在晚期夏科氏膝关节病的应用[J]. 中国矫形外科杂志, 2022, 30(3): 277-280. [Zhuang ZK, Xu ZQ, Lin XH, et al. Rotating hinged total knee arthroplasty for end-stage Charcot's joint of the knee[J]. Orthopedic Journal of China, 2022, 30(3): 277-280.] DOI: 10.3977/j.issn.1005-8478.2022.03.19.

31.Dardari D. An overview of Charcot's neuroarthropathy[J]. J Clin Transl Endocrinol, 2020, 22: 100239. DOI: 10.1016/j.jcte.2020.100239.

32.Uccioli L, Sinistro A, Almerighi C, et al. Proinflammatory modulation of the surface and cytokine pheno-type of monocytes in patients with acute Charcot foot[J]. Diabetes Care, 2010, 33(2): 350-355. DOI: 10.2337/dc09-1141.

33.Petrova NL, Dew TK, Musto RL, et al. Inflammatory and bone turnover markers in a cross-sectional and prospective study of acute Charcot osteoarthropathy[J]. Diabet Med, 2015, 32(2): 267-273. DOI: 10.1111/dme.12590.

34.王志伟, 吴学建, 朱旭, 等. 夏科氏足的病理生理和诊疗新进展[J]. 中国实用医刊, 2018, 45(3): 123-126. [Wang ZW, Wu XJ, Zhu X, et al. Pathophysiology and the progress of treatment of Charcot foot[J]. Chinese Journal of Practical Medicine, 2018, 45(3): 123-126.] DOI: 10.3760/cma.j.issn.1674-4756.2018.03.044.