Intestinal fistula complicated with Wernicke encephalopathy after radical resection for right colon cancer: a case report

Published on Dec. 30, 2024Total Views: 347 times Total Downloads: 80 times Download Mobile

Author: YUAN Zhongyuan ¹ YANG Fuhai ²  WANG Xiangyang ²

Affiliation: 1. School of Medicine, Jianghan University, Wuhan 430056, China 2. Department of Gastrointestinal Surgery, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430014, China

Keywords: Wernicke encephalopathy Radical resection for colon cancer Intestinal fistula Vitamin B1

DOI: 10.12173/j.issn.1004-4337.202410069

Reference: Yuan ZY, Yang FH, Wang XY. Intestinal fistula complicated with Wernicke encephalopathy after radical resection for right colon cancer: a case report[J]. Journal of Mathematical Medicine, 2024, 37(12): 947-952. DOI: 10.12173/j.issn.1004-4337.202410069[Article in Chinese]  Copied

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Abstract

Vitamin and mineral deficiencies are common nutritional imbalances after gastrointestinal surgery, caused by postoperative dietary restrictions, absorption disorders, and impaired digestive function. Wernicke encephalopathy is an acute neurological disease mainly due to vitamin B1 (thiamine) deficiency. It can cause severe neurological damage, and if untreated, has a mortality rate of up to 20%. Among treated patients, about 16% can fully recover. Wernicke's encephalopathy after gastrointestinal surgery is rare. This article reports a case of intestinal fistula complicated with Wernicke encephalopathy arter resection for right colon cancer. After a neurological assessment, vitamin B1 was administered, leading to an improvement in clinical symptoms. Gastrointestinal surgical fistulas can lead to vitamin B1 deficiency, thereby causing Wernicke encephalopathy, so vitamin B1 supplementation is essential for patients undergoing prolonged fasting after gastrointestinal surgery.

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