Objective  This study aimed to evaluate the dietary nutritional status and dietary inflammatory index (DII) levels of patients with chronic fatigue syndrome (CFS) and to explore the relationship between DII and fatigue.

Methods  Using a 24-hour dietary review survey to investigate the dietary nutrient intake types, quantities and time of 51 patients with CFS for three days. The energy and nutrient intake were analyzed by nutrition analysis software. The total score of the DII was calculated. The degree of fatigue in patients with CFS was evaluated by using multidimensional fatigue inventory-20 (MFI-20).

Results  The CFS patients have more protein intake and less carbohydrate intake, and the proportion of energy supply of nutrients is unreasonable, and they had a low intake of vegetable, fruit and animal-based foods. The total score of DII in the CFS patients ranged from -4.24 to 6.04, with a mean of (2.37±2.50). The more the diet tended to be pro-inflammatory, the lower its intake of nutrients with anti-inflammatory tendency was. There was no correlation between the fatigue and the DII in CFS patients (r=0.129, P=0.366). BMI was negatively correlated with DII (r=-0.287, P=0.041).

Conclusion  The CFS patient has an unreasonable diet and the diet has a high inflammatory potential. There was no correlation between fatigue and dietary inflammation index, but the data showed a certain trend, which provides reference data for inflammation effect of diet and nutrition on CFS patients.

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