Objective  To analyze the current situation and development trend of the related research about "treating lung and intestine together" in China and abroad for providing references to the inheritance and innovation of traditional Chinese medicine theory.

Method  Based on data sources from CNKI and Web of Science (WOS), relevant literature of theoretical exploration and practical application about "treating lung and intestine together" since 2000 were collected. The VOSviwer and CiteSpace software were used to visualize the publication time, journals, geographical distribution, and keywords.

Results  A total of 751 Chinese articles and 384 English articles were included. The number of publications showed an upward trend, which entered a period of rapid development after 2015. The top-ranked Chinese journal and English journal were China Journal of Traditional Chinese Medicine and Pharmacy (n=38) and Frontiers in Immunology (n=25) respectively. Beijing University of Chinese Medicine had the highest number of publications in Chinese (n=90), which had close cooperative relationships with 16 other institutions. The institution with the highest number of English publications was the Institut National de la Sante et de la Recherche Medicale and University of California System, both of which published 12 articles. Chinese and English keywords formed 12 and 7 meaningful clusters respectively in VOSviewer, and the research hotspots mainly focused on exploring classical theory, lung and large intestine-related diseases, prescriptions, mechanisms, and related factors.

Conclusion  The research about "treating lung and intestine together" has shown a generally upward development trend. The gut-lung axis, gut microbiota, and lung microbiota may still be research hotspots and frontiers in the future. Different institutions should strengthen and deepen cooperation, promote academic exchanges, and pay attention to using modern scientific and technological means to study traditional Chinese medicine theory. Additionally, efforts should be made to promote the dissemination of traditional Chinese medicine theory internationally.

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